A Terry Fox New Frontiers Program Project Grant provides support to a group of researchers conducting independent high-quality investigations in a complex area of cancer research. The purpose is to stimulate group interaction based on the premise that high impact work in complex areas of cancer research requires collaboration. The Terry Fox New Frontiers Program Project Grant is designed for researchers with complementary skills, who investigate different aspects of a given cancer relevant topic, the results of which will be realized more rapidly and efficiently than if the individual projects were to be funded as a series of independent operating grants. This long-standing funding opportunity has supported many of the best cancer research groups in Canada.
To explore new frontiers in cure-oriented cancer research by means of a group research grant.
Support under this RFA is for multidisciplinary programs of excellence that contribute to well-defined research topics of relevance to cancer. The goal of each innovative and independently fundable research project and technologies that comprise a Terry Fox New Frontiers Program Project Grant (PPG) is to provide new knowledge with the potential to transform cancer diagnosis, treatment and/or understanding of cancer biology. Proposals which address fundamental issues such as (i) hard-to-treat cancers, (ii) metastatic disease, (iii) mechanisms of disease progression and/or resistance, or (iv) cancer stem cells are welcomed in addition to other cancer-relevant topics.
This RFA supports programs comprised of a minimum of three independent researchers and their research projects, and may also include one or more technology platforms that will be used by the projects. Support is offered, commencing on July 1, 2016, for:
- New Applications of up to $750,000 per annum for a maximum of three years, and
- Renewing Applications of up to $1,500,000 per annum for a maximum of five years.
Summary of Letter of Intent Stage
As described in the competition Request for Applications (RFA), The Terry Fox Research Institute (TFRI) has created a Program Project Grant Steering Committee on Research Excellence (PPG SCORE) which will oversee this year's competition. The committee reviewed 17 letter of intent (LOIs) applications on Wednesday September 9, 2015 in Toronto. All LOIs received were from established cancer researchers proposing to study important cancer questions in novel and innovative ways. The committee has recommended that seven LOI teams be invited to prepare full applications. The competition envelope is currently capped at $15 million (or $3 million per year) which will be sufficient to fund two or three programs. The teams invited to apply are:
|Program Title ||Project Leader |
|Overcoming Treatment Failure in Lymphoid Cancer ||Connors, Joe |
|Targeting the Adaptive Molecular Landscape in Castrate-Resistant Prostate Cancer ||Gleave, Martin |
|Lung Cancer Screening ||Lam, Stephen |
|Slaying the Nemean lion – towards breast cancer precision medicine ||Lupien, Mathieu |
|Targeting clonal heterogeneity in treatment-refractory glioblastoma ||Singh, Sheila |
|Targeting the Hippo signaling pathway in cancer ||Wrana, Jeff |
|Integrated Molecular Analysis of Small Renal Masses for Identification of New Biomarkers and Therapeutic Targets ||Yousef, George |
For inquiries, please contact:
Terry Fox Research Institute | l'Institut de recherche Terry Fox
675 West 10th Avenue
Vancouver, BC V5Z 1L3 CANADA
Telephone: 1-604-675-8000 ext 7624