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How polarity regulates invasive and metastatic breast cancer

This project has been completed

Dr. Luke McCaffrey, an assistant professor with McGill University’s Department of Oncology and senior scientist with Rosalind and Morris Goodman Cancer Research Centre, will receive $441,205 over the next three years to pursue a molecular understanding of how polarity regulates invasive and metastatic cancer in order to provide insights into novel prognostic and therapeutic avenues for breast and other cancers. By identifying patterns of tumour growth, this research could point to ways to inhibit that growth. 

“It’s our goal to identify pathways that we could potentially inhibit pharmacologically so there would be a real benefit to patients down the line,” says Dr. McCaffrey, whose work involved developing new breast cancer models and imaging tools. 

Mentoring Dr. McCaffrey is Dr. William Muller, principal investigator of the Terry Fox New Frontiers Team Program Project Preclinical Models and Therapeutic Targets for Metastatic Breast Cancer. Dr. McCaffrey will also receive mentoring from other members of the team, including Drs. Morag Park, Peter Siegel and Vincent Giguere.

Mentoring Program: Terry Fox New Frontiers Team Program Project Preclinical Models and Therapeutic Targets for Metastatic Breast Cancer
Mentors/PIs: Dr. William Muller