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TFRI News | May 14, 2018

TFRI Now Seeking Applications for its 2019 Cancer Research Programs


The Terry Fox Research Institute (TFRI) is seeking applications for two of its prestigious grant programs: The Terry Fox New Frontiers Program and the Terry Fox New Investigators Awards. 

Both peer-reviewed grant programs focus on supporting excellence and collaboration in cancer research. They're main goal is to move discoveries from the laboratory to the clinic more quickly for the benefit of cancer patients.

Terry Fox New Frontiers Program

The Terry Fox New Frontiers Program Project Grants is a long?standing program involving the best cancer researchers in Canada. These programs support Canadian research teams exploring new frontiers in cancer research (i.e., breakthrough and transformative biomedical, clinical and translational research which may form the basis for innovative cancer prevention, diagnosis and/or treatment).

New Applicants
 for the Terry Fox New Frontiers Program Project Grants may be supported for a maximum of four years, with a budget of up to $400,000 in the first year followed by up to $600,000 per year for the next three years. Meanwhile, renewing applicants may receive up to $1,000,000 per annum for a maximum of six years

Current recipients include:

Program Dates funded Program lead(s)
Exploiting Pathogenic Mechanisms in Acute Leukemia for Clinical Translation 2017-2022 Karsan, Aly
Canadian Oncolytic Virus Consortium (COVCo) 2017-2022 Bell, John
Nanoparticle-Enhanced Photoacoustic Imaging for Cancer Localization and Therapeutic Guidance 2017-2022 Zheng, Gang
Delineating Therapeutic Opportunities in Triple-Negative Breast Cancer 2016-2019 Lupien, Mathieu
Targeting clonal heterogeneity in treatment-refractory glioblastoma with novel and empiric immunotherapies 2016-2019 Singh, Sheila
Targeting the Hippo Signaling Network in Cancer
2016-2019 Wrana, Jeff
Targeting the adaptive molecular landscape in castrate-resistant prostate cancer
2016-2021 Gleave, Martin
Overcoming Treatment Failure in Lymphoid Cancers 2016-2021 Connors, Joseph
Development of Stemness-Based Prognostic Biomarkers and Therapeutic Targets 2015-2020 Dick, John
Oncometabolism and the Molecular Pathways that Fuel Cancer 2015-2019 Giguere, Vincent
Killing the Hydra: genetic dissection of actionable targets required for maintenance of metastatic disease 2011-2019 Egan, Sean
A research pipeline for hypoxia-directed precision cancer medicine 1999-2019 Bristow, Robert; Wouters, Bradly
Li-Fraumeni Syndrome: Applying Genetic Determinants of Cancer Risk to Cancer Surveillance and Prevention 2015-2018 Malkin, David
Discovery and Therapeutic Development of Antibody-Based Targets in Oncology 2015-2018 Jones, Steven
Genomics of forme fruste tumours: new vistas on cancer biology and management 2010-2018 Huntsman, David

For more information
on the Terry Fox New Frontiers Program 2019 grants, including application guidelines and deadlines, please visit the award site:

Terry Fox New Investigator Awards

The Terry Fox New Investigators Awards provides research operating grant support to future leaders as they develop their independent careers in cancer research. Designed to provide a single research grant to scientific and clinical investigators within the first five years of a first faculty-level appointment in Canada, new investigators have to be sponsored and mentored by an existing Terry Fox funded program.

The 2019 Terry Fox New Investigators Awards add up to $150,000 per annum, and are tenable for three years.

Current recipients include:

Name Start/End Project
Trevor Pugh
2017-2020 Single cell dissection and non-invasive monitoring of childhood cancer
Housheng Hansen He
2017-2020 Understanding the function of circular RNA in tumour hypoxia
Frederick Antoine Mallette
Deciphering the oncogenic properties of cancer-associated IDH1/2 mutations
Peter Stirling
Functionalizing SWI/SWF chromatin remodeller mutations in rare and common tumours
Guy Ungerechts
2016-2019 Next Generation Cancer Immunovirotherapy: Heterologous oncolytic prime-boost enhanced with select immunomodulators
Ralph DaCosta
2016-2019 Investigating radiation responses of pancreatic tumours, their vasculature and microenvironment using in vivo imaging to identify new treatment strategies
William Lockwood
2016-2019 Assessing the effect of radiation from screening low dose CT scans on lung cancer development and progression
Byram Bridle
Evaluation of oncolytic immunotherapy in canine cancer trials: A stepping stone towards successful translation into human patients
Martin Hirst


Epigenetic basis of acute myeloid leukemia

Ryan Morin


Exploring Clonal Evolution in Non-Hodgkin Lymphomas Using Serial Tumour Sampling and Liquid Biopsies

Sachin Katyal
2018-2021 Targeting resistant glioblastoma multiforme rGBM) through suppression of overactive DNA repair activity
Robert Kridel
2018-2021 Dissecting biological hererogeneity in follicular lymphoma into clinically relevant molecular subtypes

For more information on the 2019 New Investigator Awards, including application guidelines and deadlines, please visit the award site: