Research Highlight|January 08, 2021 Cancer cells hibernate like bears to evade harsh chemotherapy A team led by Dr. Catherine O’Brien, a TFRI-funded scientist at the Princess Margaret Cancer Centre in Toronto, discovered that when under threat, all...
Research Highlight|December 14, 2020 Administering low-dose chemotherapy improves cancer vaccine’s effectiveness in mice models TFRI-funded researchers from the Canadian Oncolytic Virus Consortium (COVCo) have found a way to improve the efficacy of therapeutic cancer vaccines, ...
Research Highlight|December 14, 2020 Study reveals key genetic mutation that leads to the development of aggressive bone tumour Quebec-based researchers partly funded by the TFRI have discovered that a single mutation in a gene called Histone 3.3 is responsible for the developm...
Press Release|December 14, 2020 Dedicated Terry Foxer and government relations expert Carolyn Chisholm joins TFRI’s Board of Directors The Terry Fox Research Institute is pleased to announce that Carolyn Chisholm, a long-time Terry Fox supporter and an expert in federal and provincial...
Research Highlight|December 14, 2020 Study reveals unique mutational pattern in patients with early-onset pancreatic cancer TFRI-funded researchers have found that patients with early-onset pancreatic cancer have a distinct mutational pattern in a gene called CDKN2A. This d...
Research Highlight|December 14, 2020 New study reveals why some patients with myelodysplastic syndrome become resistant to treatment BC-based researchers led by Drs. Aly Karsan and Sergio Martinez-Høyer have found that mutations in two genes – TP53 and RUNX1 – are responsible for dr...
Research Highlight|December 14, 2020 Why does sex affect cancer? New study reveals oncogenomic differences between males and females A new study led by former Terry Fox New Investigator Dr. Paul Boutros reveals key differences in specific genes and in genome-wide phenomena that may ...
Research Highlight|December 14, 2020 Team turns to machine learning to predict patient response to therapy, accelerate precision medicine Dr. Gregory Czarnota and his Terry Fox team are amongst a number of pioneering researchers using machine learning to analyze images of tumours. In doi...
Research Highlight|December 10, 2020 Two New Frontiers Program Project Grant teams receive $10.9 million for research excellence, expansion to new key areas Two outstanding teams in Ontario will receive $10.9 million over the next six years to advance research into key areas of cancer development after bei...
Research Highlight|December 09, 2020 Lung study team’s findings on early detection translate into first lung cancer screening program in Canada It is a blessing to be able to see the Terry Fox Research Institute translational research program involving eight centres across Canada come to fruit...
TFRI News|December 02, 2020 Appointment to Order of Canada recognizes contributions to lymphoid cancer by former TFRI-funded researcher Dr. Joseph Connors A former researcher and oncologist at BC Cancer has been appointed as a Member of the Order of Canada for his outstanding contributions to the field o...
Research Highlight|November 30, 2020 Mapping out the mystery of blood stem cells Using state-of-the art sequencing technology, Princess Margaret scientists have revealed how stem cells are able to generate new blood cells throughou...
TFRI News|November 05, 2020 2020 Terry Fox Run Challenge: Researchers show up virtually and raise nearly $98k for cancer research TFRI-funded researchers showed up in full force for the 40th annual Terry Fox Run, raising a whopping $97,934 for cancer research.
Research Highlight|October 22, 2020 Calgary-based researchers discover new tactic to stop the growth of a deadly brain cancer The finding, published in Nature Communications, provides a new tactic in the war against cancer that involves reprogramming the immune system to do w...
Research Highlight|September 01, 2020 New study reveals mechanisms that drive chemotherapy resistance in aggressive breast cancers Targeting breast cancer cells that change and adapt to evade chemotherapy in order to survive and grow, could be a new way to treat the often deadly t...
Research Highlight|September 01, 2020 Developing precision medicine alternatives for triple negative breast cancer TFRI-funded scientists in Toronto have made a discovery that could unlock precision medicine treatments for patients diagnosed with triple negative br...
Research Highlight|August 31, 2020 New treatment possibilities for young women diagnosed with rare form of ovarian cancer A recent finding by TFRI-funded researchers in BC may offer a new treatment possibility for people diagnosed with a rare and aggressive form of ovaria...
Research Highlight|August 31, 2020 Repurposing cholesterol drugs to treat multiple myeloma A new study TFRI-funded researchers at Princess Margaret Cancer Centre found that drugs prescribed to lower blood cholesterol, known as statins, may b...
TFRI News|August 17, 2020 Marathon of Hope Cancer Centres Network operational plan continues to take shape Plans for implementation of the new pan-Canadian network to accelerate precision medicine continue to move ahead with partners and leaders from the fo...
Research Highlight|August 17, 2020 Quantifying PTEN loss could help stratify risk of relapse for patients with prostate cancer, study finds A research team in Kingston, Ontario has identified the specific threshold at which PTEN loss becomes clinically significant, presenting a new tool th...
TFRI News|August 17, 2020 Terry Fox Run 2020: Important information for researchers For the first time ever, the 2020 Terry Fox Run will be held virtually. This year’s theme, One Day, Your Way! encourages participants to be creative w...
Press Release|August 12, 2020 Medical oncologist Dr. Tony Reiman joins TFRI Executive as new Atlantic Node Leader The Terry Fox Research Institute (TFRI) is pleased to announce the appointment of Dr. Tony Reiman as its Atlantic Node Leader, representing the provin...
Research Highlight|August 05, 2020 Alberta-based brain researcher team publishes papers in two high-impact journals Members of a translational research project supported by TFRI from 2012 to 2019 continue to make an impact with two recent publications in important m...
Research Highlight|August 05, 2020 Study finds that nanobubbles can exit vascular system, bringing ultrasound-based therapies one step closer to reality Researchers have devised a method to get nanobubbles out of the vascular system intact, presenting a means by which to access and treat deep-seated tu...
Research Highlight|August 05, 2020 Researchers identify mutation associated with improved survival in Diffuse Large B-cell Lymphoma BC-based researchers have found that TMEM30A loss affects the cell membrane, allowing drugs to be delivered into cancer cells more effectively and imp...
Research Highlight|August 05, 2020 New immunotherapy shows promise in treating aggressive adult brain cancer A new CAR-T cell therapy developed by researchers in Hamilton and Toronto may help treat glioblastoma (GBM), an aggressive form of brain cancer that a...
Research Highlight|August 04, 2020 A blood test could predict who benefits from immunotherapy A test which detects changing levels of tumour fragments in the blood may be an easy, non-invasive and quick way to predict who will benefit from immu...
Research Highlight|June 23, 2020 Montreal Cancer Consortium team sheds light on why men may be genetically more prone to melanoma A new study by researchers from the Montreal Cancer Consortium is shedding new light on the role sex genes play in melanoma progression, providing new...
TFRI News|June 19, 2020 TFRI launches 2020 Terry Fox Run Challenge The Terry Fox Research Institute (TFRI) has launched its 2020 Terry Fox Run Challenge, an annual event in which our research teams look to claim top h...
TFRI News|May 28, 2020 TFRI update on COVID-19 and cancer research funding Most cancer research across Canada is curtailed due to the COVID-19 health emergency. Like other philanthropic organizations, our funding for cancer r...
Research Highlight|May 27, 2020 Team isolates rare clones destined to cause relapse within diagnosis samples of acute lymphoblastic leukemia Diagnosis relapse initiating (dRI) clones have unique characteristics that favor relapse and can be found in diagnosis samples from patients, meaning ...
Press Release|May 27, 2020 Clinical trial reveals more effective way to treat aggressive prostate cancers A clinical trial led by BC-based researchers partly funded by the TFRI has revealed that administering abiraterone acetate first, with enzalutamide af...
Research Highlight|May 27, 2020 Promising new antigens found in non-coding ovarian cancer DNA may provide clues for therapeutic vaccine Ovarian cancer researchers in Montreal are hoping newly found molecules might be used to create vaccines for patients with an aggressive form of the d...
Research Highlight|May 27, 2020 New study suggests MRI images can predict how patients with brain metastasis will respond to radiotherapy Quantitative biomarkers derived from conventional MRI in conjunction with machine learning techniques can, potentially, be used to predict outcomes fo...
Research Highlight|May 25, 2020 New study reveals genetic "scars" caused by cancer therapy A new study led by two BC-based researchers affiliated with TFRI and the Marathon of Hope Cancer Centres Network has revealed the genetic "scars" caus...
Research Highlight|May 19, 2020 Researchers identify how hormones and aging affect breast cancer in largest study of its kind After reviewing over 7,000 cancer tissues, researchers partly funded by the TFRI are shedding new light on the relationship between age-related change...
Research Highlight|May 19, 2020 Scientists identify promising immunotherapy combination for pediatric brain cancer An international team that includes TFRI-funded researchers has discovered that combining immunotherapy with a drug called tumor necrosis factor (TNF)...
Research Highlight|April 20, 2020 Pancreatic cancer researchers encouraged by new T-cell finding that identifies patients with hallmarks of an antitumour response A small subset of patients with pancreatic cancer exhibit a T-cell inflamed profile, a finding that could open the door for the potential use of immun...
TFRI News|March 25, 2020 Update on TFRI activities during pandemic We have postponed a number of important meetings such as our 9th Scientific Meeting, and the peer review meetings for our current PPG competition. TFR...
Press Release|February 18, 2020 L’Institut de recherche Terry Fox et les Instituts de recherche en santé du Canada investissent ensemble deux millions de dollars pour soutenir les travaux de nouveaux chercheurs prometteurs Cinq chercheurs de Toronto amorçant une carrière prometteuse dans le domaine du cancer recevront un total de deux millions de dollars pour mener des t...
TFRI News|February 18, 2020 The Terry Fox Research Institute and the Canadian Institutes of Health Research partner to invest $2-million to support research of promising new investigators Five promising, Toronto-based, early career cancer researchers will receive a total of $2-million to undertake research on a deadly brain cancer calle...
TFRI News|January 16, 2020 From the President’s Desk: An update on the Marathon of Hope Cancer Centres Network Dr. Victor Ling provides on update on the Marathon of Hope Cancer Centres Network and discusses what 2020 will bring for the Terry Fox Research Instit...
Research Highlight|January 15, 2020 Lung study team optimistic about new algorithm that can detect lung cancer up to three years before it forms TFRI’s Early Detection Lung Study has developed a way to help doctors predict who is at higher risk of developing the disease.
Research Highlight|January 15, 2020 Targeting the CXCL12/CXCR4 pathway could make curative radio-chemotherapy more effective, less toxic for patients with cervical cancer A groundbreaking discovery by a group of TFRI-funded scientists in Toronto is paving the way for the creation of combination therapies that could make...
Research Highlight|January 15, 2020 Goundbreaking discovery could help block metastasis for two kinds of sarcomas, including the one that claimed Terry Fox TFRI researchers have found that a family of drugs known as Class 1 HDAC inhibitors can block sarcoma metastasis in mice by hindering a cancer cell’s ...
Research Highlight|January 15, 2020 New resource could help researchers use genomic information to determine how a patient will respond to radiation therapy A new computational resource by a group of TFRI-funded researchers in Toronto may one day provide some answers about how patients respond to radiation...
Research Highlight|January 14, 2020 TFRI-funded researchers in Toronto turn 'junk' DNA into gold Mining the rich, uncharted territory of the genome or genetic material of a cancer cell has yielded gold for TFRI-funded scientists at the Princess Ma...
Research Highlight|January 14, 2020 New discovery reveals how Hodgkin lymphoma avoids attack from immune cells A team of lymphoma researchers partly funded by the TFRI has discovered a unique way in which Hodgkin lymphoma cells interact with regular immune cell...
Press Release|January 14, 2020 New member Carol Chiang brings wealth of financial experience to TFRI’s Board of Directors The Terry Fox Research Institute (TFRI) is pleased to announce that Vancouver financial leader Carol Chiang has joined its Board of Directors as a mem...
Research Highlight|January 14, 2020 Toronto-based clinical trial reveals new subtypes of advanced pancreatic cancer Toronto-based researchers partly funded by the TFRI have discovered detailed new information about the subtypes of pancreatic cancer.
Research Highlight|January 09, 2020 Virus associated with hand, foot and mouth disease helps fight lung adenocarcinomas in mice TFRI researchers have identified that Coxsackievirus Type B3, a virus commonly associated with hand, foot and mouth disease in children, can significa...
Research Highlight|January 09, 2020 Newly created synthetic cancer cells help advance understanding of leukemias For the first time ever, a team of TFRI-funded researchers has created synthetic cancer cells that are indistinguishable from T-cell acute lymphoblast...
Research Highlight|January 09, 2020 Study provides new insights on how aggressive breast cancer cells get the energy they need to grow A new study reveals how HER2-positive breast cancer hijack metabolic pathways to produce the extra energy they need to grow and spread.
Research Highlight|January 09, 2020 Team identifies four subtypes for common form of pancreatic cancer based on metabolic pathway alterations A team of Terry Fox-funded researchers has revealed that genetic alterations affecting the metabolic pathways of cancer cells drive outcomes in patien...
Research Highlight|October 16, 2019 TFRI-team creates first-of-its-kind proteogenomic resource for prostate cancer, providing key insights into the biology of tumours The resource combines genomic, epigenomic, transcriptomic and proteomic data from localized, intermediate-risk prostate cancers and sheds light on the...
Research Highlight|October 16, 2019 New finding sheds light on neuroendocrine prostate cancer progression New study reveals how RNA splicing of BHC80 promotes the development of treatment-induced neuroendocrine prostate cancer, providing potential avenue f...
Research Highlight|October 16, 2019 How this TFRI-funded team is finding inspiration in nature and harnessing the power of light to improve cancer care Eight years ago, researchers looking to improve how cancer is diagnosed and treated decided to develop a nanoparticle that mimicked how natural organi...
TFRI News|October 16, 2019 An Update from our President TFRI President and Scientific Director, Dr. Victor Ling, provides an update on how we're progressing in our efforts to make the Marathon of Hope Cance...
TFRI News|October 16, 2019 New TFRI poster and presentation templates for researchers The TFRI poster and presentation templates for researchers reflect our organization's refreshed brand identity.
TFRI News|October 15, 2019 TFRI will host special session on Marathon of Hope Cancer Centres Network at 5th CCRC meeting On Monday, November 4 we will host a special 30-minute presentation on the Marathon of Hope Cancer Centres Network.
Research Highlight|October 04, 2019 Early results from two studies provide insight into who may benefit from immunotherapies Two recent studies partly funded by the TFRI are showing results that provide key insights into how immunotherapy works, and who may benefit from it.
Research Highlight|October 04, 2019 Pan-Canadian team identifies two biomarkers that predict prostate cancer aggressiveness and bone metastasis The discoveries that the proteins p65 and CCN3 indicate cancer aggressiveness could help bridge a major gap that still exists in prostate cancer resea...
Research Highlight|October 04, 2019 Toronto-based team identifies potential target to supress leukemia stem cells Targeting a gene called INKA1 may supress leukemia stem cells (LSCs), stopping the disease in its tracks or preventing relapse in patients who have al...
Research Highlight|October 04, 2019 Collaborators identify new anti-tumour target TP73/p73 with potential to attack cancer stem-like cells and help avoid cancer relapse New discovery provides key insights into the mechanisms used by cancer cells to elude treatment and finds a new target that could be exploited to disr...
Research Highlight|October 04, 2019 Artificial intelligence helps researchers predict if breast cancer patients will respond to chemotherapy before treatment is administered A team of TFRI-funded researchers based out of the Sunnybrook Research Institute in Toronto has devised a new technique that could determine if patien...
TFRI News|October 02, 2019 Terry Fox PROFYLE research shows profiling cancer tumours in real time is giving hope to children and young adults previously out of treatment options Early results show that an innovative research program honouring Terry Fox’s legacy is providing treatment opportunities to children and young adults ...
TFRI News|September 30, 2019 2019 Terry Fox Run Challenge: TFRI research teams show immense support, raise over $80k for research TFRI-funded researchers showed up in full force for the 39th annual Terry Fox Run, adding a splash of purple to run sites across the country and raisi...
Event|August 02, 2019 Mark your Calendars: TFRI Ontario Node will host annual Research Symposium on Dec. 12, 2019 The Terry Fox Research Institute's Ontario Node is happy to announce that it will be holding its annual Research Symposium on Thursday, Dec. 12 at the...
TFRI News|July 26, 2019 TFRI Launches 2019 Terry Fox Run Challenge the TFRI is proud to launch the 2019 Terry Fox Run Challenge. Our goal for this year is to surpass the amount of money raised in 2018.
Press Release|July 11, 2019 TFRI and partners react to investment of $150M by Federal Minister of Health to create “Team Canada of Cancer Research” The federal Minister of Health, Ginette Petitpas Taylor, announced today an investment of $150 million over five years by the Government of Canada for...
Press Release|July 11, 2019 Federal Minister of Health shows government support for Marathon of Hope Cancer Centres network through $150-million investment to accelerate precision medicine The federal Minister of Health, Ginette Petitpas Taylor, announced today an investment of $150 million over five years by the Government of Canada to ...
Press Release|July 04, 2019 Two top Canadian research teams receive $12 million to solve key cancer challenges The teams, which are based in Toronto and Montreal/Ottawa, will use the funding to dive deep into the unique biology of cancer cells with the hopes of...
Press Release|July 03, 2019 Trouver dans le microenvironnement des tumeurs de nouvelles cibles thérapeutiques en vue de personnaliser les traitements contre le cancer Une équipe de spécialistes chevronnés du Princess Margaret Cancer Centre de Toronto est appelée à élargir ses travaux de recherche novateurs sur les e...
Press Release|July 02, 2019 L’Institut de recherche Terry Fox et la Fondation du cancer du sein du Québec s’unissent pour financer à hauteur de 6 M$ une équipe de chercheurs explorant de nouvelles façons de traiter le cancer du sein métastatique Grâce à un nouveau financement de six millions de dollars sur une période de six ans, une équipe de chercheurs basée à Montréal et à Ottawa tentera de...
Research Highlight|June 14, 2019 A "one-two punch" to wipe out cancerous ovarian cells A team of researchers led by former Terry Fox New Investigator Francis Rodier (University of Montreal Hospital Research Centre - CRCHUM) has developed...
Research Highlight|June 03, 2019 New finding may aid in prediction of aggressiveness of colorectal cancer The deletion of Interleukin-17 receptor (IL-17R), a receptor gene that regulates inflammation, may help predict the aggressiveness of colorectal cance...
Research Highlight|June 03, 2019 Spatial organization of immune cells within tumour microenvironment tied to survival of lung cancer patients “The main concept we wanted to demonstrate is that the spatial organization of immune and tumour cells has a clinical impact. In other words, it’s not...
Research Highlight|June 03, 2019 EZH2 inhibitors could make immunotherapies more effective for a subset of patients with diffuse large B-cell lymphoma A study by a group of BC-based scientists partly funded by the TFRI has discovered mutations responsible for changes in expression of major histocompa...
Research Highlight|June 03, 2019 New research suggests immunotherapy could help nearly 50 per cent of patients with rare mesothelioma A team of scientists partly funded by the Terry Fox Research Institute has shown that nearly half of all patients with peritoneal mesothelioma (PeM), ...
TFRI News|June 03, 2019 Update on the Marathon of Hope Cancer Centres Network There have been a number of activities under way since the Government of Canada’s announcement in March 2019 that it would provide up to $150 million ...
Research Highlight|June 03, 2019 Scientists find common brain cancer found in childhood is related to early brain development A new study on the origin and development of pediatric tumours of the cerebellum, such as medulloblastoma, has concluded that these tumours are a diso...
TFRI News|May 27, 2019 TFRI refreshes its visual identity with new logo and website The Terry Fox Research Institute is proud to announce the adoption of a brand-new visual identity as it enters its second decade of research.
TFRI News|May 27, 2019 Dr. Marla Shapiro joins TFRI Board of Directors The Terry Fox Research Institute is pleased to announce the appointment of Dr. Marla Shapiro to its board of directors.
TFRI News|May 24, 2019 Federal Government Awards $49M to Terry Fox Research Institute and Imagia led Consortium to Accelerate Medical Breakthroughs The new Digital Health and Discover Platform will greatly empower the Marathon of Hope Cancer Centres network, launched by the Terry Fox Research Inst...
Press Release|May 23, 2019 Minister Bains announces investment to accelerate medical breakthroughs that will enable truly personalized health care Today the Honourable Navdeep Bains, Minister of Innovation, Science and Economic Development, announced an investment of up to $49 million in the Digi...
Research Highlight|May 15, 2019 Team identifies new classification system for Burkitt’s Lymphoma and opens door for more precise treatments A group of scientists partly funded by the Terry Fox Research Institute has discovered a better way to classify Burkitt’s lymphoma (BL), a rare type o...
Research Highlight|May 15, 2019 Terry Fox New Investigator publishes two major papers in top scientific journals In the span of just a couple of months, TFRI New Investigator Dr. Housheng Hansen He has had major papers published in Cell and Nature Communications,...
Research Highlight|May 14, 2019 TFRI-funded scientists publish snapshot on oncolytic viruses in top scientific journal Members of a long-standing TFRI team focused on developing cancer-killing viruses have published a snapshot article summarizing this promising area of...
Research Highlight|May 14, 2019 Promising findings in pancreatic cancer study highlight the importance of genetic sequencing A study by researchers from TFRI’s Enhanced Pancreatic Cancer Profiling for Individualized Care (EPPIC) research program has led to the discovery of a...
In the Media|April 15, 2019 Media coverage across Canada highlights historic launch of the Marathon of Hope Cancer Centres Media outlets across Canada highlighted the historic launch of the Marathon of Hope Cancer Centres that took place last Friday, April 12th in St. John...
Press Release|April 11, 2019 Inspired by Terry Fox's legacy, Canadian cancer centres join forces for the first time Inspired by the legacy of Terry Fox, today the Terry Fox Research Institute and partners launched a new national network to bring together, for the fi...
Press Release|April 11, 2019 Cancer centres and researchers in Atlantic Canada join forces to provide precision medicine for cancer patients across region For the first time, leading cancer centres, hospitals and researchers in Atlantic Canada are coming together to help deliver personalized and precisio...
TFRI News|April 05, 2019 Media Advisory and Statement Regarding the Marathon of Hope Cancer Centres Network The official launch of the Marathon of Hope Cancer Centres Network will take place on Friday, April 12th in St. John's, N.L., on the same date and pla...
TFRI News|March 20, 2019 Response to the Federal Government's budget announcement regarding $150M for the Marathon of Hope Cancer Centres Network “We are thrilled with today’s announcement by the federal government to support the creation of the Marathon of Hope Cancer Centres. Under this new Te...
In the Media|March 20, 2019 Terry Fox research gets $150m for cancer data network The federal Liberals awarded $150 million to the Terry Fox Research Institute Tuesday, to create an online program for researchers to share cancer inf...
Research Highlight|February 25, 2019 Blocking Type 1 Interferon reduces negative side-effects associated with potent immunotherapy A group of scientists from the TFRI-funded Canadian Oncolytic Virus Consortium (COVCo) has discovered a new way to reduce negative side-effects associ...
In the Media|January 21, 2019 U of A oncology doctor to represent province on Terry Fox Research Institute executive When Dr. David Eisenstat decided to organize a camp charity run in the summer of 1981 inspired by the courageous cancer battle fought by Terry Fox, he...
Research Highlight|January 15, 2019 Use of mTOR inhibitors increases efficacy of herpes virus as an oncolytic therapy A new study by a team of TFRI-funded scientists has found that combining a particular strain of the herpes virus with mTOR inhibitors improves viral r...
Research Highlight|January 15, 2019 Montreal research team identifies SREBF1 as a new, targetable regulatory pathway in prostate cancer The newly discovered pathway, SREBF1, was found to be directly responsible for controlling prostate cancer cell metabolism. It can be targeted with se...
Research Highlight|January 15, 2019 Study reveals genomic differences between long- and short- term survivors of high-grade serous ovarian cancer, advancing potential for individualized treatments Researchers may be one step closer to personalizing treatments for patients with high-grade serous ovarian cancer thanks to a new study that revealed ...
Research Highlight|January 15, 2019 New finding suggests that disrupting interaction between MYC and G9a could stop cancer growth New technology has helped a TFRI-funded multidisciplinary research team identify how MYC – a key driver of human cancer – works, cracking open the pos...
Research Highlight|January 15, 2019 Pan-Canadian prostate cancer team creates robust resource tool to help clinicians with treatment decision-making A pan-Canadian prostate cancer group funded by the TFRI team has created a new tissue microarray (TMA)-based resource to assist clinicians and patholo...
Research Highlight|January 15, 2019 CEST MRI may be able to measure patient response to chemotherapy within 24 hours after first dosage TFRI researchers at Sunnybrook Hospital have found that CEST MRI technology can be used to detect cancer cell death in mice within 24 hours of receivi...
Research Highlight|January 15, 2019 Restoring stem cells to a fetal-like state could provide a therapeutic alternative for acute leukemias A team of TFRI-funded scientists in Vancouver has discovered that restoring a signaling pathway that is prevalent in fetal stem cells but dormant in a...
Research Highlight|January 15, 2019 Study shows benefit of vascular normalization in OV therapy for advanced epithelial ovarian cancer Immunologists at the University of Guelph have discovered that normalizing blood flow into tumours improves efficacy of oncolytic viruses, departing f...
TFRI News|January 15, 2019 Dr. David Eisenstat appointed Alberta Node Leader for TFRI The Terry Fox Research Institute is pleased to announce the appointment of Dr. David Eisenstat as its new node leader for the Province of Alberta.
Research Highlight|January 14, 2019 Researchers discover common markers of tumour hypoxia across 19 cancer types The study, which was partially funded by the TFRI, investigated more than 8,000 human tumours across 19 different cancer types, including prostate tum...
Press Release|December 11, 2018 Outstanding researchers from Montreal, Halifax and Toronto receive $1.35 million to find new treatments for metastatic and ovarian cancers Three outstanding early-career investigators from Montreal, Halifax and Toronto will each receive $450,000 over the next three years to explore new tr...
Research Highlight|December 03, 2018 Identification of new lymphoma sub-group by Terry Fox Research Institute-funded cancer researchers opens door for potential new treatments for hard-to-treat cancer The discovery by BC researchers of a group of bad actors ‘hidden’ within a cohort of good ones may translate into new hope for cancer patients diagnos...
Event|November 14, 2018 TFRI BC Node researchers present their work during 2018 BC Cancer Summit The Terry Fox Research Institute's BC Node will host its annual Node Day on Friday, Nov. 23, 2018 at the Sheraton Wall Centre in Vancouver.
Event|October 16, 2018 Agenda posted for TFRI's Atlantic Node 2018 Cancer Research Conference The Terry Fox Research Institute's Atlantic Node and Beatrice Hunter Cancer Research Institute will be hosting their annual Cancer Research Conference...
TFRI News|October 01, 2018 2018 Terry Fox Run Challenge: TFRI teams show immense support, raise over $90k for research TFRI-funded researchers showed up in full force for the 38th annual Terry Fox Run, adding a splash of purple to run sites across the country and raisi...
Event|September 25, 2018 TFRI Ontario Node Day to be held on December 10, 2018 The Terry Fox Research Institute's Ontario Node will be holding its annual Research Symposium on December 10, 2018 at the MaRS Auditorium (conference ...
Research Highlight|September 10, 2018 Discovery of CD33 in human cord blood cells may affect design of targeted AML therapies This new discovery provides a possible explanation of why some trials that have used CD33 as a potential target for AML therapies have shown specific ...
Research Highlight|September 10, 2018 New discovery answers long-held question about myelodysplastic syndromes In a study published in Nature Communications (June 2018), a team led by Dr. Aly Karsan (BC Cancer) suggests that the key to understanding how both bo...
Research Highlight|September 10, 2018 Co-targeting EphA2/A3 reduces rGBM tumour growth in mice models A bi-specific antibody created by a TFRI-funded team has shown great promise in reducing tumour growth in patients with recurrent glioblastoma (rGBM).
Research Highlight|September 10, 2018 How do doctors really feel about active surveillance? A new study asking health care professionals why many men with low-risk prostate cancer opt for invasive treatments instead of active surveillance rev...
Research Highlight|September 10, 2018 Team identifies CDC25 as a common therapeutic target for triple-negative breast cancer Targeting CDC25 could bring hope to patients with RB1-deficient triple-negative breast cancer (TNBC), according to Toronto-based TFRI-funded team.
Research Highlight|September 10, 2018 Deep-sea bacteria inspire researchers to develop new ways to see, treat tumours The novel dual-biomimetic system created by a TFRI-funded team could serve as a contrast agent that allows researchers to see tumours more clearly, wh...
Research Highlight|September 10, 2018 Scientists use protein found in mosquito virus to suppress RNAi pathway, opening door to make oncolytic viruses more effective By using a protein from a virus first found in Japanese mosquitoes in the 1950s, TFRI-funded researchers have discovered a new way to bypass antiviral...
Event|August 04, 2018 TFRI launches 2018 Terry Fox Run Challenge To register a team for the Terry Fox Run 2018, please visit http://www.terryfox.org/run/teams/, or join our TFRI Headquarters team captained by Dr. Vi...
TFRI News|August 02, 2018 Pilot project network teams report steady progress in first year of working together Over the past year, the Terry Fox Canadian Comprehensive Cancer Centre Network (TF4CN) has fostered unprecedented collaborations, harmonized complex r...
Research Highlight|July 11, 2018 Leukemia researchers discover genetic screening tool to predict healthy people at risk of developing aggressive form of leukemia An international team of leukemia scientists that includes TFRI-funded researchers has discovered how to predict healthy individuals at risk of develo...
Research Highlight|July 01, 2018 MCC sub-project looks to identify biomarkers that could predict success of immunotherapy for leukemia patients A group of cancer investigators from some of the top research institutions in Montreal have come together to launch a groundbreaking project focused o...
Research Highlight|July 01, 2018 Montreal immunotherapy team studying ways to overcome treatment resistance in patients with melanoma Immunologist Dr. John Stagg (Université de Montréal, CR-CHUM) tells us how he and his team will contribute to a Montreal Cancer Consortium (MCC) initi...
Research Highlight|July 01, 2018 Project team in Montreal focuses on reducing side-effects, increasing effectiveness of immune therapies for melanoma patients Dr. Watson and his team are researching how the immune system interacts with melanoma, a disease that has been proven to respond favourably to anti-PD...
In the Media|June 28, 2018 Montreal Cancer Consortium created to develop new strategies Grouping of seven hospitals and research centres will focus on immunotherapy
TFRI News|June 28, 2018 The Terry Fox Research Institute and Montreal research partners form consortium to provide more personalized treatments for cancer patients in Québec Seeking to improve treatments for 18,000 annual cancer patients, leading researchers, cancer centres and hospitals in Montreal and The Terry Fox Resea...
Press Release|June 28, 2018 L’Institut de recherche Terry Fox et leurs partenaires de recherche de Montréal forment un consortium en vue d’offrir des traitements plus personnalisés aux personnes atteintes de cancer au Québec Dans le but d’améliorer les traitements offerts aux 18 000 patients atteints de cancer traités annuellement, les meilleurs chercheurs, centres de canc...
TFRI News|June 12, 2018 Celebrate failure! says TFRI’s leader in new book celebrating Chinese Canadians Dr. Victor Ling is among several prominent Chinese Canadians featured in a newly published 180-page, full-colour book titled Celebration: Chinese Cana...
Press Release|June 05, 2018 Trois des meilleures équipes de recherche canadiennes reçoivent 13 millions de dollars pour résoudre les principaux problèmes liés au cancer Drs. Greg Czarnota (Sunnybrook Health Sciences Centre), David Malkin (Hospital for Sick Children) and David Huntsman (BC Cancer, UBC) (Click here&nb...
TFRI News|June 05, 2018 Three top Canadian research teams receive $13 million to solve key cancer challenges Three outstanding cancer research teams will receive nearly $13 million to continue their investigations into rare tumours, an inherited disorder (Li-...
Research Highlight|June 01, 2018 Harmonizing T-cell production across multiple Canadian sites will potentially bring immunotherapy trials to more patients in more places Ovarian cancer patients across Canada may soon have access to promising immunotherapy trials thanks to a new collaboration fostered by The Terry Fox C...
Research Highlight|May 17, 2018 Erectile dysfunction drugs and flu vaccine may work together to help immune system fight cancer after surgery, study finds A new study led by Dr. Rebecca Auer, a member of TFRI's Oncolytic Virus project and former recipient of a TFRI New Investigator Award, suggests that a...
Research Highlight|May 15, 2018 Breakthrough test uses ctDNA to determine treatment resistance in advanced prostate cancer patients Metastatic castration-resistant prostate cancer (mCRPC) patients are now one step closer to more personalized treatment, thanks to a new test that can...
Research Highlight|May 15, 2018 Medulloblastoma leptomeningeal metastases can also occur through the bloodstream, study finds Findings from a recent study published in Cell are breaking new ground in the pediatric brain cancer world, suggesting medulloblastoma cells can metas...
Research Highlight|May 15, 2018 Researchers develop groundbreaking targeted sequencing pipeline to further precision medicine in lymphoid cancers A cancer research team funded partly by The Terry Fox Research Institute has identified the best method for sequencing gene mutations across several o...
Research Highlight|May 15, 2018 Targeting hypoxia can, in turn, target cancer-initiating cells in colorectal tumours Targeting hypoxia can, in turn, target cancer-initiating cells (C-ICs) in colorectal cancer a study team in Toronto has found. Additionally, the team ...
Research Highlight|May 15, 2018 Blocking donor T cell–mediated TNF? signaling can enhance positive effects of stem cell transplantation A collaboration between Swiss and Canadian research institutes has shown an effective way to enhance human hematopoietic stem and progenitor cell engr...
TFRI News|May 14, 2018 TFRI Now Seeking Applications for its 2019 Cancer Research Programs The Terry Fox Research Institute (TFRI) is seeking applications for two of its prestigious grant programs: The Terry Fox New Frontiers Program and the...
In the Media|May 13, 2018 Watch: TFRI New Investigator featured on CTV Manitoba Dr. Sachin Katyal (CancerCare Manitoba) talks about his unique approach to personalized medicine for brain cancer patients.
Research Highlight|May 10, 2018 TFRI-funded researchers uncover “evolutionary arms race” between cancer and immune system A new study led by a team of TFRI-funded researchers has uncovered the mechanisms through which deadly ovarian cancer cells escape the immune system, ...
Research Highlight|May 01, 2018 Canadian leaders in tumour hypoxia shed light on the role of mTOR signalling in prostate cancer development More findings from TFRI’s prestigious hypoxia team are continuing to change the cancer research landscape when it comes to understanding the role of t...
Event|April 26, 2018 Schedule announced for Atlantic Node's Workshop on "The Many Ways to Science" TFRI's Atlantic node and the Beatrice Hunter Cancer Research Institute will hold a joint workshop on May 25 for researchers and students in Atlantic C...
In the Media|April 11, 2018 Genetic sequencing brings new hope for North Vancouver woman Personalized treatment aids in pancreatic cancer recovery
TFRI News|March 07, 2018 Terry Fox Research Institute awards prestigious grant to help Manitoba cancer researcher tackle deadly brain cancer Brain cancer research in Manitoba has received a boost with news that a local scientist has won a prestigious cancer research award from the Terry Fox...
In the Media|March 06, 2018 New Canadian research aims for tailored treatment of pancreatic cancer Canadian scientists are teaming up with the Terry Fox Research Institute (TFRI) to lead a new $5-million personalized treatment initiative.
Press Release|March 06, 2018 Canadian pancreatic cancer research team provides personalized medicine, new hope to patients Canadian pancreatic cancer researchers are joining forces under a Terry Fox initiative bringing new hope for patients with this deadly disease.
Research Highlight|February 15, 2018 Therapeutic target EZH2 discovered for aggressive, untreatable ovarian cancer affecting young women A Vancouver team led by TFRI-funded investigator Dr. David Huntsman has discovered an important therapeutic target for treating small cell carcinoma o...
Research Highlight|February 15, 2018 Made-in-Canada model for detecting lung cancer saves lives, is a world leader A pan-Canadian TFRI team of cancer researchers has developed a predictive model for detecting early-stage lung cancer in high-risk individuals with si...
Research Highlight|February 15, 2018 Nuclear mTOR acts as a transcriptional regulator of metabolism in prostate cancer, groundbreaking study finds A recent study by TFRI’s cancer metabolism group suggests nuclear mTOR (a kinase) also works as a transcriptional regulator of metabolism in the proli...
Research Highlight|February 15, 2018 Vanadium compounds enhance efficacy of oncolytic viruses when used in combination therapy A new class of compounds is generating excitement for its ability to enhance the efficacy of oncolytic viruses (OVs) and to stimulate the immune respo...
Research Highlight|February 15, 2018 Ultrasound-stimulated microbubbles enhance radiation effect on prostate cancer cells What if there was a way to make cancer cells more susceptible to radiation therapy without damaging healthy cells? New findings from Toronto researche...
Press Release|February 15, 2018 Study finds mitochondrial mutations drive prostate cancer aggression While nuclear mutations are widely acknowledged as a driver of cancer tumours, the role of maternally inherited mitochondrial genome mutations has not...
TFRI News|February 08, 2018 2017 Marathon of Hope Lecture Series As part of its 10th anniversary celebration, TFRI presented a session titled The Marathon of Hope Lecture Series at the Canadian Cancer Research Confe...
Event|January 19, 2018 2017 TFRI Ontario Node Day Photos The annual Terry Fox Research Institute’s Ontario Node Research Symposium took place Monday, Dec. 4, 2017 at the MaRS Discovery Centre in Toronto. Ph...
Research Highlight|January 03, 2018 New study shows viruses and checkpoint inhibitors work together to cure resistant breast cancer in mice A new study led by TFRI-funded researchers at The Ottawa Hospital (TOH) and the University of Ottawa suggests that a combination of two immunotherapie...
TFRI News|December 07, 2017 Milestone Videos: TFRI Celebrates 10th Anniversary This was a big year for the Terry Fox Research Institute: 2017 marked our 10th anniversary. Here are two videos we created to celebrate this milestone...
Press Release|November 24, 2017 Canadian pediatric researchers, funders join forces, commit $16.4M to give young people across the country a fighting chance against cancer For the first time in Canadian history, more than 30 pediatric cancer research and funding organizations have joined forces through Terry Fox PROFYLE,...
In the Media|November 23, 2017 CancerCare Manitoba joins research project that offers hope for kids with rare cancers PROFYLE project brings together experts from across Canada to network, discover new treatments
In the Media|November 23, 2017 Canada-wide program aims to get young cancer patients faster access to new therapies If Terry Fox were diagnosed today, he would fall among the 20 per cent of young cancer patients who run out of treatment options. But now, patients li...
In the Media|November 23, 2017 Children out of cancer treatment options offered hope by new Terry Fox program 'It presents options and time,' says mother of 8-year-old girl now on new cancer drug
TFRI News|October 26, 2017 B.C. Lung Screen Trial recruiting 2,000 people for cancer screening study The B.C. Lung Screen Trial at Vancouver General Hospital is currently recruiting 2,000 individuals from the Lower Mainland who are between 55 and 80 y...
Research Highlight|October 18, 2017 Terry Fox research team’s model for detecting lung cancer saves lives, is a world leader: study A pan-Canadian team of cancer researchers has developed a predictive model for detecting early-stage lung cancer in high-risk individuals with signifi...
TFRI News|September 06, 2017 Four premier TFRI investigators will present Marathon of Hope talks at CCRC TFRI is pleased to announce that it will be presenting a concurrent session (D6 in program) at the upcoming Canadian Cancer Research Conference featur...
TFRI News|September 06, 2017 TFRI's 8th ASM focuses on potential of precision medicine TFRI’s one-day 8th Annual Scientific Meeting on Saturday, Nov. 4 in Vancouver will feature talks related to the theme of the potential of precision me...
TFRI News|September 06, 2017 It’s not too late to join a Terry Fox Run research team! The annual Terry Fox Run is just around the corner and our purple-shirted research teams, their friends and families will be out in full force again t...
Research Highlight|September 06, 2017 Canadian, international researchers find new candidate drivers, subtype diversity in study of whole-genome landscape for children’s brain cancer A new study has analyzed hundreds of sequenced medulloblastoma (MB) samples, identifying new targets that could give children with this disease less h...
Research Highlight|September 06, 2017 Vancouver team identifies new class of molecules with potential in treating metastatic prostate cancer A recent study by a prolific TFRI-funded team has demonstrated that disrupting ERG transcriptional activity is sufficient to suppress the major charac...